|
PAD4 Inhibitor Therapy for Managing Heart Failure and Diabetic Complications
PAD4 Inhibitor Therapy for Managing Heart Failure and Diabetic Complications
Background
Heart failure and diabetic complications, including cardiomyopathy and nephropathy, are significant global health challenges affecting millions. Heart failure, specifically heart failure with preserved ejection fraction (HFpEF), is characterized by impaired heart...
Published: 3/25/2026
|
Updated: 3/25/2026
|
Inventor(s):
Keywords(s):
Category(s): Technology Classifications > Invention Type > Therapeutics > Small Molecule, Technology Classifications > Invention Type > Therapeutics, Technology Classifications > Disease Area > Cardiology, Technology Classifications > Disease Area > Cardiovascular
|
|
Elastic Multi-Electrode ECG Strip Pad for Accurate Cardiac Monitoring
Elastic Multi-Electrode ECG Strip Pad for Accurate Cardiac Monitoring
Background
The heart generates electrical signals which travel through a patient’s skin. Electrocardiographs (ECGs) monitor these electrical signals in order to provide information about a patient’s heart. To capture this electrical information, sensors, in the form...
Published: 4/2/2026
|
Updated: 12/5/2025
|
Inventor(s): Michael Agus, R Burnett, Lynne Hamilton
Keywords(s):
Category(s): Technology Classifications > Disease Area > Cardiology, Technology Classifications > Invention Type > Medical Devices
|
|
TAZ gene replacement therapy
TAFAZZIN gene replacement therapy
Background
Barth Syndrome (BTHS) is an X-linked, potentially lethal genetic disease that affects about 1 in 0.3 to 0.4 million live births. It is characterized by cardiomyopathy, skeletal myopathy, neutropenia, growth delay, poor feeding, and organic aciduria, with cardiac complications and neutropenia being the...
Published: 3/30/2026
|
Updated: 3/10/2025
|
Inventor(s): William Pu, Suya Wang
Keywords(s):
Category(s): Technology Classifications > Disease Area > Rare Diseases, Technology Classifications > Invention Type > Therapeutics > Gene Therapy, Technology Classifications > Disease Area > Cardiology
|
|
In vivo high efficiency somatic homology directed repair
In vivo high-efficiency somatic homology directed repair
Background
Recent advances in genome sequencing techniques and analysis methods have significantly accelerated the ability to catalog and map genetic factors associated with a diverse range of biological functions and diseases, but precise genome targeting technologies are needed to enable...
Published: 3/30/2026
|
Updated: 2/23/2024
|
Inventor(s): William Pu, Nathan VanDusen, Yanjiang Zheng
Keywords(s):
Category(s): Technology Classifications > Disease Area > Cardiology, Technology Classifications > Invention Type > Therapeutics > Gene Therapy
|
|
Pinnate Assembly of Artificial Chordae for Heart Valve Cleft Repair
Pinnate Assembly of Artificial Chordae for Heart Valve Cleft Repair
A surgical implant based on artificial chordae, that can effectively close cleft cardiac valves
Background
Aortic valve cleft is a rare disease that can be degenerative, congenital, or age-related. It may be present with or without other heart defects and can lead to serious aortic...
Published: 6/26/2025
|
Updated: 5/5/2023
|
Inventor(s): Pedro del Nido, Peter Hammer, Mossab Saeed, David Hoganson, Sitaram Emani, Christopher Baird
Keywords(s): Cardiology, Cardiovascular, Surgery
Category(s): Technology Classifications > Invention Type, Technology Classifications > Invention Type > Medical Devices, Technology Classifications > Disease Area, Technology Classifications > Disease Area > Rare Diseases, Technology Classifications > Disease Area > Cardiology, Technology Classifications > Disease Area > Surgery
|
|
Device and Methods to Approximate Papillary Muscles for Cardiac Valve Repair and Ventricular Remodeling
Device and Methods to Approximate Papillary Muscles for Cardiac Valve Repair and Ventricular Remodeling
Devices and methods for approximating the papillary muscles in mitral and tricuspid valves
Background
The papillary muscles are attached to the mitral and tricuspid valves and prevent the prolapse of the valve leaflet. Outward dislocation of these...
Published: 6/26/2025
|
Updated: 3/7/2023
|
Inventor(s): Pedro del Nido, Eoin O'Cearbhaill, Haruo Yamauchi, Nikolay Vasilyev, Maria Nunes-Pereira
Keywords(s):
Category(s): Technology Classifications > Invention Type, Technology Classifications > Invention Type > Medical Devices, Technology Classifications > Disease Area, Technology Classifications > Disease Area > Surgery, Technology Classifications > Disease Area > Cardiology
|
|
Coaptation Mapping Technology for Heart Valve Assessment
Coaptation Mapping Technology for Heart Valve Assessment
A device that can be used to assess the valve operation intra-operatively while the heart is open
Background
Approximately 60,000 heart valve repair operations are performed annually in the US. Typically, the surgeon determines the valve defect and the required repair using preoperative echocardiography....
Published: 6/26/2025
|
Updated: 3/6/2023
|
Inventor(s): David Hoganson, Peter Hammer
Keywords(s):
Category(s): Technology Classifications > Disease Area, Technology Classifications > Disease Area > Surgery, Technology Classifications > Disease Area > Cardiology, Technology Classifications > Invention Type, Technology Classifications > Invention Type > Medical Devices
|
|
Instrument for Beating-heart Mitral Valve Chordal Replacement to Treat Prolapse
Instrument for Beating-heart Mitral Valve Chordal Replacement to Treat Prolapse
A novel optically-guided device that significantly enhances the convenience and accuracy of neochordae placement
Background
Mitral valve prolapse (MVP) affects 2-3% of the population. In MVP, one or more of the chordae tendineae, which support the leaflets during systole,...
Published: 7/22/2025
|
Updated: 3/6/2023
|
Inventor(s): Pierre Dupont, Karl Price, Gustavo Arnal
Keywords(s):
Category(s): Technology Classifications > Invention Type, Technology Classifications > Invention Type > Medical Devices, Technology Classifications > Invention Type > Medical Devices > Instruments, Technology Classifications > Disease Area, Technology Classifications > Disease Area > Cardiology, Technology Classifications > Disease Area > Surgery
|
|
Apparatus and Method for Intraoperative Assessment of Aortic or Pulmonary Valve Repair
Apparatus and Method for Intraoperative Assessment of Aortic or Pulmonary Valve Repair
An apparatus that enables the surgeon to pressurize and visually inspect the valve to assess the efficacy of the surgical repairs
Background
The semilunar (i.e., pulmonary and aortic) valves of the heart perform the critical task of regulating the flow of blood...
Published: 7/22/2025
|
Updated: 3/6/2023
|
Inventor(s): Peter Hammer, Douglas Perrin, Pedro del Nido, Nikolay Vasilyev, David Hoganson, Nick Kneier, Eric Penchansky, Ignacio Berra
Keywords(s):
Category(s): Technology Classifications > Invention Type, Technology Classifications > Invention Type > Medical Devices, Technology Classifications > Invention Type > Medical Devices > Instruments, Technology Classifications > Disease Area, Technology Classifications > Disease Area > Cardiology, Technology Classifications > Disease Area > Surgery
|
|
Real-time Monitoring of Breathing and Heart Function: an Alert System for Medical Emergencies
Real-time Monitoring of Breathing and Heart Function: an Alert System for Medical Emergencies
Effective monitoring and early warning system that can detect an advancing respiratory or cardiac emergency
Background
Many patients suffering from chronic conditions such as asthma and COPD are at risk of experiencing potentially fatal emergencies. These...
Published: 3/20/2026
|
Updated: 2/15/2023
|
Inventor(s): Benjamin Matthews, Christopher Norve
Keywords(s):
Category(s): Technology Classifications > Invention Type, Technology Classifications > Invention Type > Medical Devices, Technology Classifications > Disease Area, Technology Classifications > Disease Area > Cardiology, Technology Classifications > Disease Area > Pulmonary
|
