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The adjuvant combination PVP-AF04 enhances the antibody response towards SARS-CoV antigens
The adjuvant combination PVP-AF04 enhances the antibody response towards SARS-CoV antigens
Background
As of 2024, SARS-CoV-2 has caused over 1 million deaths in the United States and more than 7 million worldwide. As the virus continues to mutate, it is important to advance immunization efforts to combat the virus’s effects, especially...
Published: 3/24/2026
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Updated: 5/8/2024
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Inventor(s): Ofer Levy, Yoshine Saito, Francesco Borriello, David Dowling, Timothy Yu
Keywords(s):
Category(s): Technology Classifications > Disease Area > Infectious Disease, Technology Classifications > Disease Area > Infectious Disease > COVID-19, Technology Classifications > Invention Type > Vaccines > Adjuvants
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SARS-COV-2 Antigen Nanoparticles and Uses Thereof
SARS-COV-2 Antigen Nanoparticles and Uses Thereof
Background
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), a novel betacoronavirus, has caused a global health crisis and still poses a substantial risk to public health, leading to over 103 million reported infections in the United States and over 774 million worldwide since 2019. The...
Published: 3/24/2026
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Updated: 2/13/2024
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Inventor(s): Ofer Levy, Francesco Boriello, David Dowling, Sirano Dhe-Pagnon, Hyuk-Su Seo, David Scott, Frederic Feru
Keywords(s):
Category(s): Technology Classifications > Disease Area > Immunology, Technology Classifications > Disease Area > Infectious Disease, Technology Classifications > Disease Area > Infectious Disease > COVID-19, Technology Classifications > Invention Type > Vaccines, Technology Classifications > Invention Type > Vaccines > Adjuvants
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Production of a stabilized ectodomain trimer of SARS-CoV-2 spike protein
Production of a stabilized ectodomain trimer of SARS-CoV-2 spike protein
Background
The COVID-19 pandemic highlighted the exceptional ability of certain viruses to genetically mutate, altering themselves in order evade the immune response of their host. In RNA-viruses such as SARS-CoV-19, a single strand of RNA is responsible for reprogramming...
Published: 3/30/2026
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Updated: 2/13/2024
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Inventor(s): Bing Chen, Yongfei Cai, Hanqin Peng
Keywords(s):
Category(s): Technology Classifications > Disease Area > Infectious Disease > COVID-19, Technology Classifications > Invention Type > Vaccines
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Intubation Shield - a foldable plastic shield that can be placed on the patient to protect the intubator and other healthcare workers in the room during intubation.
Intubation Shield: A foldable plastic shield to protect the patient and healthcare workers during intubation
Background
The coronavirus disease 2019 (COVID-19) pandemic has profoundly impacted global human health and is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This novel virus was first identified in China in...
Published: 3/27/2026
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Updated: 8/14/2023
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Inventor(s): Farokh Demehri, Heung Kim, Robert Crum, Brianna Slatnick, Kyle Wu, Alexander Yang, Pete Kovatsis, Nathaniel Tighe, Jonathan Durgin
Keywords(s): Medical Device, Respiratory
Category(s): Technology Classifications > Invention Type, Technology Classifications > Invention Type > Medical Devices, Technology Classifications > Disease Area, Technology Classifications > Disease Area > Infectious Disease, Technology Classifications > Disease Area > Infectious Disease > COVID-19
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Instranasal Delivery of Apilimod and Nafamostat for the Treatment of COVID
Intranasal Delivery of Apilimod and Nafamostat for the Treatment of COVID
Unmet Need
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused the coronavirus disease 2019 (COVID-19) pandemic and has profoundly impacted global human health. Since its initial discovery in 2019, several viral variants have caused additional outbreaks...
Published: 6/26/2025
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Updated: 5/23/2023
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Inventor(s): Tomas Kirchhausen, Alex Kreutzberger, Giuseppe Balistreti
Keywords(s): Combination Therapy, Drug Repurposing
Category(s): Technology Classifications > Invention Type, Technology Classifications > Invention Type > Therapeutics, Technology Classifications > Invention Type > Therapeutics > Small Molecule, Technology Classifications > Disease Area, Technology Classifications > Disease Area > Infectious Disease, Technology Classifications > Disease Area > Infectious Disease > COVID-19
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Antisense oligonucleotides that suppress SARS-CoV-2 replication
Antisense Oligonucleotides that Suppress SARS-CoV-2 Replication
Antisense oligonucleotides that suppress SARS-CoV-2 replication by targeting the 5’ untranslated region of SARS-CoV-2
Background
The coronavirus disease 2019 (COVID-19) pandemic has profoundly impacted global human health and is caused by the severe acute respiratory syndrome coronavirus...
Published: 9/26/2025
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Updated: 1/6/2023
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Inventor(s): Hao Wu, Longfei Wang, Setu Vora
Keywords(s):
Category(s): Technology Classifications > Invention Type, Technology Classifications > Invention Type > Therapeutics, Technology Classifications > Disease Area, Technology Classifications > Disease Area > Infectious Disease, Technology Classifications > Disease Area > Infectious Disease > COVID-19, Technology Classifications > Invention Type > Therapeutics > ASOs
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