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Advanced Method for Producing Natural Killer Cells from Pluripotent Stem Cells for Cancer Immunotherapy
Advanced Method for Producing Natural Killer Cells from Pluripotent Stem Cells for Cancer Immunotherapy
Background
Cancer remains a significant global health challenge, with millions of individuals affected by various types of the disease each year. The standard of care typically involves surgery, chemotherapy, and radiation therapy, often resulting...
Published: 3/26/2026
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Updated: 10/6/2025
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Inventor(s): George Daley, Deepak Jha, Mohammad Najia
Keywords(s):
Category(s): Technology Classifications > Disease Area > Oncology, Technology Classifications > Invention Type > Therapeutics, Technology Classifications > Invention Type > Therapeutics > Cell Therapy
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Production of T-cells using engineered soluble DLL4 ligands
Production of T cells using engineered soluble DLL4 ligands
Background
Chimeric Antigen Receptor T-cell (CAR T-cell) therapies are a therapeutic tool for the treatment of several types of cancers, most notably lymphomas and leukemia. Healthy T cells are taken from the patient’s blood, cultured in the laboratory to induce differentiation, and...
Published: 3/26/2026
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Updated: 11/20/2024
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Inventor(s): Rubul Mout, Ran Jing, George Daley, Stephen Blacklow, David Baker, Emily Egan
Keywords(s):
Category(s): Technology Classifications > Invention Type > Therapeutics > Cell Therapy, Technology Classifications > Disease Area > Immunology, Technology Classifications > Disease Area > Hematology
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The Xeno-Free Red Blood Cell Differentiation Media
The Xeno-Free Red Blood Cell Differentiation Media
The in vitro differentiation of human iPSCs into adult RBCs using a novel Xeno-free Erythroid Differentiation Media (XF-EDM)
Background
Donor-derived blood products are in high-demand in clinical medicine to maintain the health of patients lacking in key blood components such as red blood cells (RBCs)....
Published: 3/26/2026
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Updated: 3/7/2023
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Inventor(s): Trista North, George Daley, Ashlee Conway, Tolulope Rosanwo, Thomas Williamson
Keywords(s):
Category(s): Technology Classifications > Invention Type, Technology Classifications > Invention Type > Therapeutics, Technology Classifications > Invention Type > Therapeutics > Cell Therapy, Technology Classifications > Disease Area, Technology Classifications > Disease Area > Hematology
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