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Choroid plexus targeted NKCC1 gene therapy for the treatment of hydrocephalus
Choroid Plexus Targeted NKCC1 Gene Therapy for the Treatment of Hydrocephalus
AAV-targeted augmentation of NKCC1 expression to reverse blood-induced ventriculomegaly and increased CSF clearance capacity
Background
A subset of infants and adults with hemorrhagic stroke and intraventricular hemorrhage (IVH) ultimately develop a life-threatening accumulation...
Published: 3/27/2026
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Updated: 4/18/2023
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Inventor(s): Maria Lehtinen, Cameron Sadegh, Huixin Xu, Ryann Fame, Jason Sutin, Benjamin Warf, Pei-Yi (Ivy) Lin
Keywords(s):
Category(s): Technology Classifications > Invention Type, Technology Classifications > Invention Type > Therapeutics, Technology Classifications > Invention Type > Therapeutics > Gene Therapy, Technology Classifications > Disease Area, Technology Classifications > Disease Area > Neurology
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