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Application of novel enterococcus pore-forming toxins
Advancing Treatment for Antibiotic-Resistant Infections with Enterococcus Pore-Forming Toxin Technology
Background
Enterococcus faecalis and Enterococcus faecium have emerged as significant contributors to multidrug-resistant (MDR) infections, posing a substantial threat to public health due to their inherent and acquired resistance to antibiotics....
Published: 3/20/2026
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Updated: 10/6/2025
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Inventor(s): Min Dong, Xiaozhe Xiong, Songhai Tian
Keywords(s):
Category(s): Technology Classifications > Invention Type > Research Tools > Protein (Research Tool), Technology Classifications > Invention Type > Therapeutics > Peptide, Technology Classifications > Disease Area > Infectious Disease
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Targeting Neurogenic Inflammation to Combat Clostridioides difficile Infections
Targeting Neurogenic Inflammation to Combat Clostridioides difficile Infections
Background
Clostridioides difficile infection (CDI) is a prevalent gastrointestinal condition in developed countries, notably causing approximately half a million cases and 29,000 deaths annually in the United States alone. This infection arises from a disruption in the...
Published: 3/30/2026
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Updated: 7/28/2025
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Inventor(s): Meenakshi Rao, Melissa Musser, Min Dong
Keywords(s):
Category(s): Technology Classifications > Disease Area > Gastroenterology, Technology Classifications > Invention Type > Therapeutics, Technology Classifications > Invention Type > Therapeutics > Peptide
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Peptide-based Inhibitor for Treating Chronic Viral and Autoimmune Inflammatory Diseases
Peptide-based Inhibitor for Treating Chronic Viral and Autoimmune Inflammatory Diseases
A novel peptide-based inhibitor of Rig-I-like receptor (RLR)-mediated signal transduction for therapeutic modulation of the immune response
Background
Rig-I-like receptors (RLRs) have emerged as critical sentinels of viral infection, surveying the cytosol of all...
Published: 6/26/2025
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Updated: 2/14/2023
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Inventor(s): Jonathan Kagan
Keywords(s):
Category(s): Technology Classifications > Invention Type, Technology Classifications > Invention Type > Therapeutics, Technology Classifications > Disease Area, Technology Classifications > Disease Area > Autoimmune, Technology Classifications > Invention Type > Therapeutics > Peptide
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