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Biofilm Matrix Boosted Vaccine
Biofilm Matrix Boosted Vaccine
Background
Bacterial biofilm formation is a process in which bacteria adhere to a surface, creating single or multilayer structures. The biofilm matrix consists of exopolysaccharides, proteins, and DNA. In contrast to the conventional belief that biofilm exopolysaccharides primarily serve as adhesive materials for binding...
Published: 3/20/2026
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Updated: 3/10/2025
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Inventor(s): Paula Watnick, Julie Liao
Keywords(s):
Category(s): Technology Classifications > Disease Area > Infectious Disease, Technology Classifications > Invention Type > Therapeutics > Drug Delivery
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Novel Antibiotic from a Costa Rican Fungus
Novel Antibiotic from a Costa Rican Fungus
Small-molecule antibiotic with activity against commonly drug-resistant species
Background
Antibiotic-resistant microbes have become a global problem, with an estimated 48,000 deaths attributed to resistant microbes in the U.S. and Europe alone. The constant threat of the development of resistance has led...
Published: 9/26/2025
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Updated: 5/5/2023
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Inventor(s): Paula Watnick, Patrick Ymele-Leki, Jon Clardy, Shugeng Cao
Keywords(s): Antibiotic, Research Tool, Small Molecule, Therapeutic
Category(s): Technology Classifications > Invention Type, Technology Classifications > Invention Type > Therapeutics, Technology Classifications > Invention Type > Therapeutics > Small Molecule, Technology Classifications > Disease Area, Technology Classifications > Disease Area > Infectious Disease
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Innovative Uses of Biofilms for Protein Delivery, Vaccine Development, and Infectious Disease Treatment
Innovative Uses of Biofilms for Protein Delivery, Vaccine Development, and Infectious Disease Treatment
Innovative use of biofilms as a flexible platform for protein delivery and vaccine development
Background
A biofilm is a microbial community attached to various biological or non-biological surfaces and is held in place by an extracellular...
Published: 3/20/2026
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Updated: 3/6/2023
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Inventor(s): Paula Watnick, Cedric Absalon
Keywords(s):
Category(s): Technology Classifications > Invention Type > Therapeutics
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