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Intravenous Microbubbles for Oxygenation
Intravenous Microbubbles for Oxygenation
Background
Severe hypoxia, characterized by insufficient oxygen delivery, poses a critical medical challenge impacting millions globally each year. Conditions such as cardiac arrest, lung injury, airway obstruction, traumatic brain injury, and birth asphyxia often lead to rapid onset of tissue damage or organ...
Published: 3/6/2026
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Updated: 3/3/2026
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Inventor(s):
Keywords(s):
Category(s): Technology Classifications > Disease Area > Fetal/Newborn Medicine, Technology Classifications > Invention Type > Therapeutics > Drug Delivery, Technology Classifications > Disease Area > Emergency Medicine
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Macrophage Immunomodulation by Mesenchymal Stem Cell Exosome Treatment and Restoration of Lung Architecture in Models of Bronchopulmonary Dysplasia
Macrophage Immunomodulation by Mesenchymal Stem Cell Exosome Treatment and Restoration of Lung Architecture in Models of Bronchopulmonary Dysplasia
Background
Bronchopulmonary dysplasia (BPD) is a chronic lung disease of premature infants related to oxygen exposure or mechanical ventilation of the developing, immature lungs. BPD occurs approximately...
Published: 3/24/2026
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Updated: 12/20/2024
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Inventor(s): Stella Kourembanas, S. Alex Mitsialis
Keywords(s):
Category(s): Technology Classifications > Disease Area > Pulmonary, Technology Classifications > Disease Area > Immunology, Technology Classifications > Disease Area > Fetal/Newborn Medicine, Technology Classifications > Invention Type > Therapeutics > Cell Therapy
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Transamniotic Nucleic Acid Therapy
Trans-amniotic Nucleic Acid Therapy
Background
Nucleic acids like DNA and mRNA can be customized and administered for reprogramming cell functions to treat specific disorders or for immunization. With the advances in fetal diagnosis during pregnancy and advances in gene therapy using mRNA, it became possible to design mRNA therapies to treat...
Published: 3/27/2026
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Updated: 8/14/2023
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Inventor(s): Dario Fauza
Keywords(s):
Category(s): Technology Classifications > Disease Area > Fetal/Newborn Medicine, Technology Classifications > Invention Type > Therapeutics, Technology Classifications > Invention Type > Therapeutics > Drug Delivery
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Passive Perinatal Immunotherapy via Transamniotic Antibody Delivery
Passive Perinatal Immunotherapy via Transamniotic Antibody Delivery
A non-invasive method that reduces the risk of alloimmune disorders and neurological complications
Background
Limitations in the placental transfer of antibodies from the mother to the fetus can render the fetus vulnerable to a range of serious infections. Administration of therapeutic...
Published: 6/26/2025
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Updated: 2/15/2023
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Inventor(s): Dario Fauza, Ashlyn Whitlock, Daniel Labuz
Keywords(s):
Category(s): Technology Classifications > Invention Type, Technology Classifications > Invention Type > Therapeutics, Technology Classifications > Invention Type > Therapeutics > Drug Delivery, Technology Classifications > Disease Area, Technology Classifications > Disease Area > Fetal/Newborn Medicine
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Curated Gene List for Diagnosis of Sudden Unexpected Death in Pediatrics (SUDP)
Curated Gene List for Diagnosis of Sudden Unexpected Death in Pediatrics (SUDP)
A list of 203 genes has been curated for use in the post-mortem investigation of a child who has died with unexplained causes
Background
Sudden Unexplained Death in Pediatrics (SUDP) is an all-encompassing term for sudden deaths in children that remain unexplained after...
Published: 9/4/2025
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Updated: 1/6/2023
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Inventor(s): Richard Goldstein, Ingrid Holm, Annapurna Poduri, Catherine Brownstein, Gerard Berry
Keywords(s): Dataset, Diagnostics, Rare Disease, SUDP
Category(s): Technology Classifications > Invention Type, Technology Classifications > Invention Type > Diagnostics, Technology Classifications > Disease Area, Technology Classifications > Disease Area > Fetal/Newborn Medicine
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