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Methods and compositions for tauopathy diagnosis and treatment
Methods and Compositions for Tauopathy Diagnosis and Treatment
Specific cleavage characteristics of Tau seed competence associated with stress and inflammation in neurons in Alzheimer’s disease.
Background
The monomeric Tau is a soluble cytosolic protein that can aggregate under pathological conditions to form highly organized, disease-specific...
Published: 9/16/2025
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Updated: 6/30/2023
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Inventor(s): Judith Steen, Pieter Beerepoot, Long Cheng, Hanno Steen, Mukesh Kumar, Waltraud Mair, Hendrik Wesseling
Keywords(s): Brain, Diagnostics, Neurology
Category(s): Technology Classifications > Disease Area, Technology Classifications > Disease Area > Neurology, Technology Classifications > Invention Type > Diagnostics
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Rapid MRI Acquisition By Image Reconstruction Augmented with Inter-voxel Constraints
Rapid MRI Acquisition By Image Reconstruction Augmented with Inter-voxel Constraints
A novel and effective algorithm to reduce the geometry-factor artifacts in parallel magnetic resonance imaging.
Background
Magnetic resonance imaging (MRI) is one of the most versatile and safest imaging modalities with numerous applications in medicine. One of the...
Published: 3/30/2026
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Updated: 6/7/2023
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Inventor(s): Simon Warfield, Ali Pouryazdanpanah Kermani, Onur Afacan
Keywords(s): Diagnostics, Oncology, Radiology
Category(s): Technology Classifications > Disease Area, Technology Classifications > Disease Area > Orthopedics, Technology Classifications > Invention Type, Technology Classifications > Invention Type > Medical Devices, Technology Classifications > Invention Type > Medical Devices > Imaging
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Video-based automated detection of generalized tonic-clonic seizures using deep learning
Video-based automated detection of generalized tonic-clonic seizures using deep learning
Background
Detecting epileptic seizures in a timely manner is crucially important as early detection can prevent complications such as secondary injuries, falls, and neurological damage. Early detection also allows for timely treatment and care that can stop or...
Published: 6/30/2025
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Updated: 6/1/2023
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Inventor(s): Christian Meisel, Tobias Loddenkemper
Keywords(s): Diagnostics, Imaging, Neurology
Category(s): Technology Classifications > Invention Type, Technology Classifications > Invention Type > Diagnostics, Technology Classifications > Disease Area, Technology Classifications > Disease Area > Neurology, Technology Classifications > Disease Area > Neurology > Epilepsy
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Improved characterization of white matter fascicles using cube and sphere diffusion MRI
Improved Characterization of White Matter Fascicles using Cube and Sphere Diffusion MRI
A novel diffusion MRI acquisition scheme that can better characterize each white matter fascicle
Background
The characterization of the white matter fascicles in the brain poses a significant challenge. Models that seek to represent the contribution from multiple...
Published: 3/30/2026
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Updated: 5/10/2023
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Inventor(s): Simon Warfield, Benoit Scherrer, Moti Freiman
Keywords(s): Diagnostics, Neurology, Radiology
Category(s): Technology Classifications > Disease Area, Technology Classifications > Disease Area > Neurology, Technology Classifications > Invention Type, Technology Classifications > Invention Type > Medical Devices, Technology Classifications > Invention Type > Medical Devices > Imaging
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Method for corneal afferent imaging in concussion and migraine to assess outcomes for focal and systemic therapeutics.
Method for Diagnosing and Monitoring Concussions
Technology Overview
Concussions are notoriously difficult to accurately diagnose by conventional systems and methods which can lead to long-term implications on whether a patient in treated correctly.
Conventional methods require either subjective judgements by health care professionals or...
Published: 3/20/2026
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Updated: 5/4/2023
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Inventor(s): David Borsook, Eric Moulton
Keywords(s): Diagnostics, Imaging, Neurology, Trauma
Category(s): Technology Classifications > Disease Area, Technology Classifications > Disease Area > Neurology, Technology Classifications > Invention Type > Diagnostics
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Biomarkers of Neuropathic Pain
Biomarkers of Neuropathic Pain
They can be used to access neuropathic pain, diagnostics, clinical trials and in assessing therapeutic intervention for treating pain
Background
Pain is a sensory disturbance that is very difficult to measure accurately based on patients' subjective reports. There is an enormous need for objective and sensitive...
Published: 9/16/2025
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Updated: 2/15/2023
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Inventor(s): Clifford Woolf, Alban Latremoliere, Alexandre Chloe, Thomas Scammell
Keywords(s): Diagnostics, ZZCommon
Category(s): Technology Classifications > Disease Area, Technology Classifications > Disease Area > Neurology, Technology Classifications > Invention Type, Technology Classifications > Invention Type > Biomarkers
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Curated Gene List for Diagnosis of Sudden Unexpected Death in Pediatrics (SUDP)
Curated Gene List for Diagnosis of Sudden Unexpected Death in Pediatrics (SUDP)
A list of 203 genes has been curated for use in the post-mortem investigation of a child who has died with unexplained causes
Background
Sudden Unexplained Death in Pediatrics (SUDP) is an all-encompassing term for sudden deaths in children that remain unexplained after...
Published: 9/4/2025
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Updated: 1/6/2023
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Inventor(s): Richard Goldstein, Ingrid Holm, Annapurna Poduri, Catherine Brownstein, Gerard Berry
Keywords(s): Dataset, Diagnostics, Rare Disease, SUDP
Category(s): Technology Classifications > Invention Type, Technology Classifications > Invention Type > Diagnostics, Technology Classifications > Disease Area, Technology Classifications > Disease Area > Fetal/Newborn Medicine
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