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Methods and compositions for tauopathy diagnosis and treatment
Methods and Compositions for Tauopathy Diagnosis and Treatment
Specific cleavage characteristics of Tau seed competence associated with stress and inflammation in neurons in Alzheimer’s disease.
Background
The monomeric Tau is a soluble cytosolic protein that can aggregate under pathological conditions to form highly organized, disease-specific...
Published: 9/16/2025
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Updated: 6/30/2023
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Inventor(s): Judith Steen, Pieter Beerepoot, Long Cheng, Hanno Steen, Mukesh Kumar, Waltraud Mair, Hendrik Wesseling
Keywords(s): Brain, Diagnostics, Neurology
Category(s): Technology Classifications > Disease Area, Technology Classifications > Disease Area > Neurology, Technology Classifications > Invention Type > Diagnostics
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Video-based automated detection of generalized tonic-clonic seizures using deep learning
Video-based automated detection of generalized tonic-clonic seizures using deep learning
Background
Detecting epileptic seizures in a timely manner is crucially important as early detection can prevent complications such as secondary injuries, falls, and neurological damage. Early detection also allows for timely treatment and care that can stop or...
Published: 6/30/2025
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Updated: 6/1/2023
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Inventor(s): Christian Meisel, Tobias Loddenkemper
Keywords(s): Diagnostics, Imaging, Neurology
Category(s): Technology Classifications > Invention Type, Technology Classifications > Invention Type > Diagnostics, Technology Classifications > Disease Area, Technology Classifications > Disease Area > Neurology, Technology Classifications > Disease Area > Neurology > Epilepsy
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Improved characterization of white matter fascicles using cube and sphere diffusion MRI
Improved Characterization of White Matter Fascicles using Cube and Sphere Diffusion MRI
A novel diffusion MRI acquisition scheme that can better characterize each white matter fascicle
Background
The characterization of the white matter fascicles in the brain poses a significant challenge. Models that seek to represent the contribution from multiple...
Published: 3/30/2026
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Updated: 5/10/2023
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Inventor(s): Simon Warfield, Benoit Scherrer, Moti Freiman
Keywords(s): Diagnostics, Neurology, Radiology
Category(s): Technology Classifications > Disease Area, Technology Classifications > Disease Area > Neurology, Technology Classifications > Invention Type, Technology Classifications > Invention Type > Medical Devices, Technology Classifications > Invention Type > Medical Devices > Imaging
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Method for corneal afferent imaging in concussion and migraine to assess outcomes for focal and systemic therapeutics.
Method for Diagnosing and Monitoring Concussions
Technology Overview
Concussions are notoriously difficult to accurately diagnose by conventional systems and methods which can lead to long-term implications on whether a patient in treated correctly.
Conventional methods require either subjective judgements by health care professionals or...
Published: 3/20/2026
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Updated: 5/4/2023
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Inventor(s): David Borsook, Eric Moulton
Keywords(s): Diagnostics, Imaging, Neurology, Trauma
Category(s): Technology Classifications > Disease Area, Technology Classifications > Disease Area > Neurology, Technology Classifications > Invention Type > Diagnostics
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