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Barcode for dementia: A molecular signature of Alzheimer’s disease and other tauopathies using mass spectrometry
Diagnostics of various Tauopathies
Background
Dementia and other cognitive disorders are serious medical issues that are of increasing concern as the global population ages. Dementia is not a specific disease, but rather a descriptive term for a collection of symptoms that can be caused by several disorders affecting the brain. People with...
Published: 3/24/2026
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Updated: 6/3/2024
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Inventor(s): Judith Steen, Hanno Steen, Jan Muntel
Keywords(s):
Category(s): Technology Classifications > Invention Type > Diagnostics, Technology Classifications > Invention Type > Biomarkers, Technology Classifications > Disease Area > Neurology
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Utilization of CerebroSpinal Fluid biomarkers for accurate identification of Alzheimer’s Disease
Utilization of CerebroSpinal Fluid biomarkers for accurate identification of Alzheimer’s Disease
Background
Alzheimer’s disease (AD) is the sixth-leading cause of death in the United States. It represents a major health challenge due to the following:
Population aging is associated with increased prevalence of dementia, with...
Published: 3/27/2026
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Updated: 7/17/2023
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Inventor(s): Hanno Steen, Patrick Van Zalm, Judith Steen
Keywords(s): CNS
Category(s): Technology Classifications > Disease Area, Technology Classifications > Disease Area > Neurology, Technology Classifications > Invention Type, Technology Classifications > Invention Type > Biomarkers
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Methods and compositions for tauopathy diagnosis and treatment
Methods and Compositions for Tauopathy Diagnosis and Treatment
Specific cleavage characteristics of Tau seed competence associated with stress and inflammation in neurons in Alzheimer’s disease.
Background
The monomeric Tau is a soluble cytosolic protein that can aggregate under pathological conditions to form highly organized, disease-specific...
Published: 9/16/2025
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Updated: 6/30/2023
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Inventor(s): Judith Steen, Pieter Beerepoot, Long Cheng, Hanno Steen, Mukesh Kumar, Waltraud Mair, Hendrik Wesseling
Keywords(s): Brain, Diagnostics, Neurology
Category(s): Technology Classifications > Disease Area, Technology Classifications > Disease Area > Neurology, Technology Classifications > Invention Type > Diagnostics
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