|
Treatment of Endometriosis pain and lesions with the use of CGRP/RAMP1 blockade and other novel targets
Treatment of Endometriosis pain and lesions with the use of CGRP/RAMP1 blockade and other novel targets
Background
Endometriosis is a chronic inflammatory disease characterized by the growth of tissue outside of the uterus, typically on the ovaries and fallopian tubes. This condition is associated with chronic pain and, in extreme cases, may lead...
Published: 3/6/2026
|
Updated: 3/6/2026
|
Inventor(s):
Keywords(s): Endometriosis
Category(s): Technology Classifications > Disease Area > Reproductive Health, Technology Classifications > Invention Type > Novel Targets
|
|
Targeting the Super Elongation Complex to Prevent Hematopoietic Stem Cell Expansion and Blood Cancer Risk
Targeting the Super Elongation Complex to Prevent Hematopoietic Stem Cell Expansion and Blood Cancer Risk
Background
It is estimated that over 1.7 million people in the United States are living with or in remission from blood cancers such as leukemias, lymphomas, myeloma, and myeloproliferative neoplasms (MPNs), and approximately 192,070 new cases...
Published: 3/26/2026
|
Updated: 12/19/2025
|
Inventor(s): Vijay Sankaran, Jiawei Zhao, Liam Cato
Keywords(s): Blood Cancer
Category(s): Technology Classifications > Disease Area > Hematology/Oncology, Technology Classifications > Invention Type > Novel Targets
|
|
Copper depletion for treatment of cancer in the brain (as a primary or secondary site)
Targeting Copper Metabolism to Improve Cancer Therapy Efficacy
Background
Acute Lymphoblastic Leukemia (ALL), one of the most common childhood cancers, is a type of cancer that originates in the bone marrow and can spread to various parts of the body, including the central nervous system (CNS) through cerebrospinal fluid. This can lead to deadly...
Published: 3/27/2026
|
Updated: 12/17/2025
|
Inventor(s): Naama Kanarek, Alan Wong
Keywords(s): Cancer
Category(s): Technology Classifications > Disease Area > Oncology, Technology Classifications > Invention Type > Novel Targets
|
|
Innovative Therapeutic Approach for Treating Thrombocytopenia Using DNA Damage Repair Inhibitors
Innovative Therapeutic Approach for Treating Thrombocytopenia Using DNA Damage Repair Inhibitors
Background
Thrombocytopenia is a dangerous condition where the number of platelets in the blood is too low (less than 150 billion per liter), increasing the risk of serious bleeding. This condition may arise in certain immune disorders after chemotherapy,...
Published: 3/30/2026
|
Updated: 12/5/2025
|
Inventor(s): Joseph Italiano, Kellie Machlus, Roelof Bekendam, Andrew Stone
Keywords(s): Thrombocytopenia
Category(s): Technology Classifications > Disease Area > Hematology/Oncology, Technology Classifications > Invention Type > Novel Targets
|
|
Novel Targets in Ophthalmology
Novel Targets in Ophthalmology
Background
Invasive cancer remains a predominant cause of mortality globally, responsible for approximately 13% of all deaths annually. As the global population continues to age, cancer rates have surged, highlighting a critical need for advanced therapeutic approaches. Traditional cancer treatments focus on intrinsic...
Published: 3/30/2026
|
Updated: 12/5/2025
|
Inventor(s):
Keywords(s): Diabetes
Category(s): Technology Classifications > Disease Area > Ophthalmology, Technology Classifications > Invention Type > Novel Targets
|
|
Targeting ZNF410 for fetal hemoglobin induction in beta-hemoglobinopathies
Targeting ZNF410 for fetal hemoglobin induction in beta-hemoglobinopathies
Background
β-hemoglobinopathies, such as sickle cell disease and β-thalassemias, are genetic disorders characterized by defective hemoglobin production, resulting in anemia and impaired oxygen delivery. These conditions affect millions worldwide, posing significant...
Published: 3/26/2026
|
Updated: 11/29/2025
|
Inventor(s): Daniel Bauer, Divya Vinjamur
Keywords(s):
Category(s): Technology Classifications > Disease Area > Hematology/Oncology, Technology Classifications > Invention Type > Novel Targets
|
|
Targeting prosaposin (pSAP) to dendritic cells as novel cancer immunotherapy
Targeting prosaposin (pSAP) to dendritic cells as novel cancer immunotherapy
Background
Antigen-specific T cell responses are central to protection against cancer. Abundance and proper function of immune cells, including lymphocytes and antigen-presenting cells such as dendric cells (DCs), at the tumor site are vital for effective immunity and control...
Published: 3/23/2026
|
Updated: 11/29/2025
|
Inventor(s): Florian Winau
Keywords(s):
Category(s): Technology Classifications > Disease Area > Hematology/Oncology, Technology Classifications > Disease Area > Oncology, Technology Classifications > Invention Type > Novel Targets
|
|
Therapeutic modulation of genes in myeloid lineage cells and uses thereof in ophthalmology
Novel Targets for Innovative Retinopathy Treatment
Background
Retinopathies are a group of retinal diseases characterized by progressive loss of visual acuity, often leading to blindness. These diseases can be triggered by genetic conditions such as retinitis pigmentosa or by environmental factors like retinopathy of prematurity (ROP). Approximately...
Published: 4/2/2026
|
Updated: 10/6/2025
|
Inventor(s): Ye Sun, Tianxi Wang
Keywords(s):
Category(s): Technology Classifications > Disease Area > Ophthalmology, Technology Classifications > Invention Type > Novel Targets
|
|
Controlling pH-Dependent Condensates for Cellular Response
Controlling pH-Dependent Condensates for Cellular Response
Background
Inflammation is a vital part of the body’s defense mechanisms, ensuring homeostasis and protecting the integrity of tissues and organs. However, excessive inflammatory responses can lead to severe tissue damage. Despite existing treatments, the fine control over inflammatory...
Published: 3/30/2026
|
Updated: 10/6/2025
|
Inventor(s): Xu Zhou, Zhongyang Wu
Keywords(s):
Category(s): Technology Classifications > Disease Area > Immunology, Technology Classifications > Invention Type > Novel Targets
|
|
Targeting cytokine secretion to ameliorate fibrosis in myeloproliferative neoplasms
Targeting cytokine secretion to ameliorate fibrosis in myeloproliferative neoplasms
Background
Myelofibrosis is a bone marrow cancer characterized by disruptions in blood cell production. This leads to several symptoms such as anemia and an increased risk of infection and bleeding. Primary and secondary myelofibrosis, a subset of myeloproliferative...
Published: 3/30/2026
|
Updated: 3/10/2025
|
Inventor(s): Joseph Italiano, Isabelle Becker
Keywords(s):
Category(s): Technology Classifications > Disease Area > Hematology, Technology Classifications > Invention Type > Novel Targets
|
