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Methods to detect clonal somatic mutation from deep panel sequencing and bulk RNA-seq data and their application on identifying pathogenic role of somatic mutations in cell proliferation genes of Alzheimer brains
Methods for assessing neuroinflammation using somatic mutations in Alzheimer's Disease
Background
Alzheimer’s disease (AD) is a neurodegenerative condition that affects about 1 in 9 Americans aged 65 and older, with almost 7 million people currently affected and 14 million expected to be affected by 2060. One of the early pathogenic processes...
Published: 3/23/2026
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Updated: 4/3/2025
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Inventor(s): Christopher Walsh, Zinan Zhou, Alice Lee, (August) Yue Huang
Keywords(s): Neurodegeneration
Category(s): Technology Classifications > Disease Area > Neurology, Technology Classifications > Invention Type > Biomarkers, Technology Classifications > Invention Type > Diagnostics, Technology Classifications > Disease Area > Neurology > Alzheimer's Disease
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