Search Results - neurodegeneration

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Method for Identifying Genomic Age via Single-Nucleotide Variants in Single Cell Neurons

Method for Identifying Genomic Age via Single-Nucleotide Variants in Single Cell Neurons Background Aging in humans brings increased incidence of nearly all diseases, including neurodegeneration. Markers of DNA damage increase in the brain with age, and genetic progeroid diseases such as Cockayne syndrome (CS) and Xeroderma pigmentosum (XP), both...

Published: 3/23/2026 | Updated: 12/5/2025 | Inventor(s): Christopher Walsh, Rachel Rodin, Michael Coulter, Peter Park, Craig Bohrson, Alison Barton, Minseok Kwon, Michael Lodato

Keywords(s): Neurodegeneration

Category(s): Technology Classifications > Disease Area > Neurology, Technology Classifications > Invention Type > Biomarkers, Technology Classifications > Invention Type > Diagnostics

Methods to detect clonal somatic mutation from deep panel sequencing and bulk RNA-seq data and their application on identifying pathogenic role of somatic mutations in cell proliferation genes of Alzheimer brains

Methods for assessing neuroinflammation using somatic mutations in Alzheimer's Disease Background Alzheimer’s disease (AD) is a neurodegenerative condition that affects about 1 in 9 Americans aged 65 and older, with almost 7 million people currently affected and 14 million expected to be affected by 2060. One of the early pathogenic processes...

Published: 3/23/2026 | Updated: 4/3/2025 | Inventor(s): Christopher Walsh, Zinan Zhou, Alice Lee, (August) Yue Huang

Keywords(s): Neurodegeneration

Category(s): Technology Classifications > Disease Area > Neurology, Technology Classifications > Invention Type > Biomarkers, Technology Classifications > Invention Type > Diagnostics, Technology Classifications > Disease Area > Neurology > Alzheimer's Disease