Search Results - mustafa+sahin

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Compounds Treating AP-4 Associated Hereditary Spastic Paraplegia

Compounds Treating AP-4 Associated Hereditary Spastic Paraplegia Background Hereditary Spastic Paraplegia (HSP) is a group of inherited neurological disorders characterized by progressive spasticity, weakness, and gait abnormalities and affects approximately 5-10 per 100,000 individuals worldwide. Among its subtypes, Adaptor Protein Complex 4 (AP-4)-related...

Published: 3/23/2026 | Updated: 7/28/2025 | Inventor(s): Darius Ebrahimi-Fakhari, Mustafa Sahin, Masato Satoh, Jed Hubbs

Keywords(s): Hereditary Spastic Parapeligia, Movement Disorder, Neuromuscular Disorder

Category(s): Technology Classifications > Disease Area > Neurology, Technology Classifications > Disease Area > Rare Diseases, Technology Classifications > Invention Type > Therapeutics > Small Molecule

Heat Shock Machinery as a Druggable Target in Tuberous Sclerosis Complex

Heat Shock Machinery as a Druggable Target in Tuberous Sclerosis Complex A treatment for Tuberous Sclerosis as well as other neuropsychiatric disorders with altered cilia Background Tuberous Sclerosis Complex (TSC) is a neurogenetic disorder that leads to the formation of tumors in many different organs including the brain, eyes, heart, kidney, and...

Published: 6/26/2025 | Updated: 2/14/2023 | Inventor(s): Alessia Di Nardo, Mustafa Sahin

Keywords(s): Rare Disease, Therapeutic, Therapeutics:Novel Molecules:Small molecules

Category(s): Technology Classifications > Disease Area, Technology Classifications > Disease Area > Rare Diseases, Technology Classifications > Disease Area > Neurology, Technology Classifications > Invention Type, Technology Classifications > Invention Type > Novel Targets