Search Results - pei-yi+(ivy)+lin

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Microglia for scar-less healing, protection, and regeneration in the CNS

Microglia for scar-less healing, protection, and regeneration in the CNS Background Neuron injuries associated with neurodegenerative diseases, neuroinflammation, or physical spinal cord injury have very limited therapeutic options. These pathological conditions are often permanent and include cognitive decline, persistent physical pain, paralysis,...

Published: 10/6/2025 | Updated: 5/28/2025 | Inventor(s): Zhigang He, Yi Li, Xuelian He

Keywords(s):

Category(s): Technology Classifications > Disease Area > Neurology, Technology Classifications > Invention Type > Therapeutics > Cell Therapy

Choroid plexus targeted NKCC1 gene therapy for the treatment of hydrocephalus

Choroid Plexus Targeted NKCC1 Gene Therapy for the Treatment of Hydrocephalus AAV-targeted augmentation of NKCC1 expression to reverse blood-induced ventriculomegaly and increased CSF clearance capacity Background A subset of infants and adults with hemorrhagic stroke and intraventricular hemorrhage (IVH) ultimately develop a life-threatening accumulation...

Published: 3/27/2026 | Updated: 4/18/2023 | Inventor(s): Maria Lehtinen, Cameron Sadegh, Huixin Xu, Ryann Fame, Jason Sutin, Benjamin Warf, Pei-Yi (Ivy) Lin

Keywords(s):

Category(s): Technology Classifications > Invention Type, Technology Classifications > Invention Type > Therapeutics, Technology Classifications > Invention Type > Therapeutics > Gene Therapy, Technology Classifications > Disease Area, Technology Classifications > Disease Area > Neurology