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Controlling pH-Dependent Condensates for Cellular Response
Controlling pH-Dependent Condensates for Cellular Response
Background
Inflammation is a vital part of the body’s defense mechanisms, ensuring homeostasis and protecting the integrity of tissues and organs. However, excessive inflammatory responses can lead to severe tissue damage. Despite existing treatments, the fine control over inflammatory...
Published: 3/30/2026
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Updated: 10/6/2025
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Inventor(s): Xu Zhou, Zhongyang Wu
Keywords(s):
Category(s): Technology Classifications > Disease Area > Immunology, Technology Classifications > Invention Type > Novel Targets
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Microglia for scar-less healing, protection, and regeneration in the CNS
Microglia for scar-less healing, protection, and regeneration in the CNS
Background
Neuron injuries associated with neurodegenerative diseases, neuroinflammation, or physical spinal cord injury have very limited therapeutic options. These pathological conditions are often permanent and include cognitive decline, persistent physical pain, paralysis,...
Published: 10/6/2025
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Updated: 5/28/2025
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Inventor(s): Zhigang He, Yi Li, Xuelian He
Keywords(s):
Category(s): Technology Classifications > Disease Area > Neurology, Technology Classifications > Invention Type > Therapeutics > Cell Therapy
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Specialized adeno-associated virus for central nervous system gene therapy
Specialized adeno-associated virus for central nervous system gene therapy
Background
Unlike other cell types in the human body, nerve cells (neurons) have an extremely limited ability to replace themselves through division following damage to the nervous system. Most injuries and diseases of the central nervous system (CNS) involve damage to axons,...
Published: 9/16/2025
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Updated: 6/9/2023
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Inventor(s): Zhigang He, Xue Yao, Zicong Zhang, Benedikt Brommer
Keywords(s): CNS, Gene Therapy, Therapeutic, Trauma
Category(s): Technology Classifications > Disease Area, Technology Classifications > Disease Area > Neurology, Technology Classifications > Invention Type, Technology Classifications > Invention Type > Therapeutics, Technology Classifications > Invention Type > Therapeutics > Drug Delivery
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