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Targeting the ATP/P2X7R axis to prevent and treat type 1 diabetes, allograft rejection, lung fibrosis and aging
Targeting the ATP/P2X7R axis to prevent and treat type 1 diabetes, allograft rejection, lung fibrosis and aging
Background
Insulin therapy, the current standard treatment for type 1 diabetes (T1D) cannot fully prevent the severe complications related to the disease which include kidney failure and coronary heart disease. Successful islet transplantation...
Published: 3/6/2026
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Updated: 4/11/2025
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Inventor(s):
Keywords(s):
Category(s): Technology Classifications > Disease Area > Autoimmune, Technology Classifications > Disease Area > Immunology, Technology Classifications > Disease Area > Transplant, Technology Classifications > Invention Type > Therapeutics, Technology Classifications > Invention Type > Therapeutics > Small Molecule
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Cytokine and Cellular Biomarkers for Identification of Ulcerative Colitis and Crohn's Disease using Mass Cytometry
Cytokine and Cellular Biomarkers for Identification of Ulcerative Colitis and Crohn's Disease using Mass Cytometry
Background
Inflammatory bowel disease (IBD) is a chronic condition that can lead to long-lasting intestinal inflammation associated with significant local and systemic morbidity as well as a high social and economic burden....
Published: 3/30/2026
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Updated: 2/23/2024
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Inventor(s): Scott Snapper, Yelizaveta (Liza) Konnikova, Vanessa Mitsialis
Keywords(s):
Category(s): Technology Classifications > Disease Area > Autoimmune, Technology Classifications > Disease Area > Gastroenterology, Technology Classifications > Invention Type > Diagnostics
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Mesenchymal Stromal Cell Exosomes for Thymic Dysfunction in Newborns
Mesenchymal Stromal Cell Exosomes for Thymic Dysfunction in Newborns
Background
Since the thymus is an essential organ for the production and maturation of specific immune T-cells, poor thymus development early in life can lead to multiple diseases related to immunological disorders. These diseases can manifest early, with an increased propensity...
Published: 3/23/2026
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Updated: 7/11/2023
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Inventor(s): Stella Kourembanas, S. Alex Mitsialis
Keywords(s): Immunology, Newborn Medicine
Category(s): Technology Classifications > Invention Type, Technology Classifications > Invention Type > Therapeutics, Technology Classifications > Invention Type > Therapeutics > Drug Delivery, Technology Classifications > Disease Area, Technology Classifications > Disease Area > Autoimmune
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Peptide-based Inhibitor for Treating Chronic Viral and Autoimmune Inflammatory Diseases
Peptide-based Inhibitor for Treating Chronic Viral and Autoimmune Inflammatory Diseases
A novel peptide-based inhibitor of Rig-I-like receptor (RLR)-mediated signal transduction for therapeutic modulation of the immune response
Background
Rig-I-like receptors (RLRs) have emerged as critical sentinels of viral infection, surveying the cytosol of all...
Published: 6/26/2025
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Updated: 2/14/2023
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Inventor(s): Jonathan Kagan
Keywords(s):
Category(s): Technology Classifications > Invention Type, Technology Classifications > Invention Type > Therapeutics, Technology Classifications > Disease Area, Technology Classifications > Disease Area > Autoimmune, Technology Classifications > Invention Type > Therapeutics > Peptide
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