|
An in vivo method for diversifying the functions of therapeutic antibodies
An in vivo method for diversifying the functions of therapeutic antibodies
Background
Antibodies are one of the fastest growing drug classes with a major impact particularly in oncology, autoimmunity and chronic inflammatory diseases. These products must meet stringent criteria of target specificity and affinity for their clinical application....
Published: 3/23/2026
|
Updated: 4/3/2024
|
Inventor(s): Frederick Alt, Ming Tian, Hwei-Ling Cheng, Suvi Jain
Keywords(s):
Category(s): Technology Classifications > Invention Type > Research Tools, Technology Classifications > Invention Type > Research Tools > Antibody
|
|
MEMPHIS: Modular Evaluation of immunogenicity using Multi-Platform Human In vitro Systems
MEMPHIS: Modular Evaluation of immunogenicity using Multi-Platform Human In vitro Systems
Background
Though vaccination is one of the greatest accomplishments of modern medicine, there are still challenges to the production of perfectly effective vaccines. These challenges include weakened response by the vaccinated individual’s immune system...
Published: 3/24/2026
|
Updated: 5/31/2023
|
Inventor(s): Simon van Haren, Ofer Levy, Guzman Sanchez-Schmitz, David Dowling
Keywords(s): Drug Delivery, Immunology, Infectious Disease, Vaccine
Category(s): Technology Classifications > Invention Type, Technology Classifications > Invention Type > Research Tools, Technology Classifications > Invention Type > Research Tools > Assay, Technology Classifications > Invention Type > Vaccines, Technology Classifications > Disease Area, Technology Classifications > Disease Area > Immunology, Technology Classifications > Disease Area > Infectious Disease
|
|
Rapid Methods for Precise Validation of Germline and Mosaic Genetics Mutations
Rapid Methods for Precise Validation of Germline and Mosaic Genetics Mutations
This invention provides a rapid, precise, and sensitive approach for identifying and validating genetic mutations
Background
Previous methods and studies have clearly shown the important role of mosaic mutations in disease pathogenesis but quantifying the exact level...
Published: 3/9/2026
|
Updated: 3/10/2023
|
Inventor(s): Ryan Doan, Christopher Walsh
Keywords(s):
Category(s): Technology Classifications > Invention Type, Technology Classifications > Invention Type > Research Tools, Technology Classifications > Invention Type > Research Tools > Assay
|
|
Anisotropic Material Testing Device
Anisotropic Material Testing Device
A series of force-controlled multiaxial loading devices for the purpose of characterizing bio-materials
Background
The stress-testing of biomaterials is crucial for the evaluation of their durability and suitability as medical implants. It is pivotal to simulate the forces that biomaterials will be exposed to under...
Published: 7/22/2025
|
Updated: 1/6/2023
|
Inventor(s): David Hoganson, Peter Hammer, Nick Kneier, Christopher Payne
Keywords(s): ZZCommon
Category(s): Technology Classifications > Invention Type, Technology Classifications > Invention Type > Research Tools, Technology Classifications > Disease Area, Technology Classifications > Disease Area > Cardiology
|
