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Microbiota Therapy acts via RORγt Regulatory T Cells to Enforce Oral Tolerance in Food Allergy
Microbiota Therapy acts via RORγt Regulatory T Cells to Enforce Oral Tolerance in Food Allergy
Background
The role of dysbiosis (an imbalance in the microbiome) in food allergy (FA) is unclear. However, recent data from Dr. Chatila’s research group at Boston Children’s Hospital has shown that gut dysbiosis is seen in infants with...
Published: 3/30/2026
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Updated: 2/14/2025
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Inventor(s): Talal Chatila, Azza Abdel-Gadir, Emmanuel Stephen Victor, Rima Rachid
Keywords(s):
Category(s): Technology Classifications > Invention Type > Therapeutics > Microbiome, Technology Classifications > Invention Type > Therapeutics, Technology Classifications > Disease Area > Immunology > Allergy
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Novel Bacteriotherapies for the prevention and treatment of Food Allergy
Novel Bacteriotherapies for the prevention and treatment of Food Allergies
Background
Most food allergies are acquired in the first years of life, indicating a critical role for early childhood exposures in disease pathogenesis. Reduced bacterial diversity and an impaired ratio of specific bacteria in infancy have been associated with food sensitization,...
Published: 3/20/2026
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Updated: 7/11/2023
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Inventor(s): Talal Chatila, Azza Abdel-Gadir, Emmanuel Stephen Victor, Rima Rachid, Lynn Bry, Georg Gerber
Keywords(s): Allergy, Common, Food Allergy, Immunology
Category(s): Technology Classifications > Invention Type, Technology Classifications > Invention Type > Therapeutics, Technology Classifications > Invention Type > Therapeutics > Microbiome, Technology Classifications > Disease Area, Technology Classifications > Disease Area > Immunology > Allergy
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Salicin based gut microbiome bacteria and enzymes
Salicin based gut microbiome bacteria and enzymes
Background
Inflammatory bowel disease (IBD) pertains to chronic inflammation of the gastrointestinal (GI) tract, and is classified either as ulcerative colitis, which commonly affects the large intestine and rectum, or Crohn’s disease, which affects the small intestine. While the exact cause...
Published: 6/26/2025
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Updated: 5/31/2023
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Inventor(s): Gavin Kuziel, Seth Rakoff-Nahoum
Keywords(s): Infectious Disease, Nutrition
Category(s): Technology Classifications > Invention Type, Technology Classifications > Invention Type > Therapeutics, Technology Classifications > Disease Area, Technology Classifications > Disease Area > Gastroenterology, Technology Classifications > Invention Type > Therapeutics > Microbiome
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