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TLR7/8 Ligands for Use in Opioid Vaccines
TLR7/8 Ligands for Use in Opioid Vaccines
Ligands with the potential for preventing fatal overdose of opioid users and protect against or treat Opioid Use Disorder patients
Technology Overview
Building on their work as part of the Precision Vaccines Program, researchers in the Levy lab have developed a method of enhancing immune response to anti-opioid...
Published: 3/24/2026
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Updated: 3/24/2026
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Inventor(s): Ofer Levy, David Dowling, Dheeraj Soni, Sharon Levy, Jay Evans, Marco Pravetoni
Keywords(s): Immunology, Therapeutic, ZZCommon, ZZTherapeutics:Vaccines
Category(s): Technology Classifications > Invention Type, Technology Classifications > Invention Type > Vaccines, Technology Classifications > Disease Area, Technology Classifications > Disease Area > Immunology
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TLR7/8 Adjuvant Overcomes Newborn Hyporesponsiveness to Pneumococcal Conjugate Vaccine
TLR7/8 Adjuvant Overcomes Newborn Hyporesponsiveness to Pneumococcal Conjugate Vaccine
The molecule 3M-052 offers effective immunization with one birth dose, representing a new paradigm in early life vaccine development
Technology Overview
Infection is the most common cause of mortality in early life, and immunization is the most promising biomedical...
Published: 3/24/2026
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Updated: 3/6/2023
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Inventor(s): Ofer Levy, David Dowling, Jay Evans, Helene Brazin-Lee, David Burkhart, Alyson Smith
Keywords(s): Immunology, Therapeutic, ZZCommon, ZZTherapeutics:Vaccines
Category(s): Technology Classifications > Invention Type, Technology Classifications > Invention Type > Vaccines, Technology Classifications > Disease Area, Technology Classifications > Disease Area > Infectious Disease
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STING Agonists as Immunomodulators and Vaccine Adjuvants
STING Agonists as Immunomodulators and Vaccine Adjuvants
STING agonists proven to be effective vaccine adjuvants and immunomodulators in newborns
Background
Infectious diseases are the leading cause of morbidity and mortality in early life and immunization is a key preventive strategy. Vaccine adjuvants can enhance, prolong, and modulate immune responses...
Published: 3/30/2026
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Updated: 3/6/2023
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Inventor(s): Ofer Levy, Carlo Pietrasanta, David Dowling, Francesco Borriello
Keywords(s): Immunology, Therapeutic, ZZCommon, ZZTherapeutics:Vaccines
Category(s): Technology Classifications > Invention Type, Technology Classifications > Invention Type > Vaccines, Technology Classifications > Disease Area, Technology Classifications > Disease Area > Infectious Disease
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