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(4498, 4327, 4286, 4284, 4039, 3815, 3550, 3497, 4313, 3346, 3207, 2928, 1680) Prolonged Anesthesia/ Liposomal Formations
*4498 just added- needs NCD update
Liposomal/Prolonged Anesthetic Formulations
Background
In the realm of drug delivery, liposomes are recognized for their ability to enhance site-targeting, protect drugs from degradation, and provide controlled release with lower toxicity compared to conventional methods. Despite these advantages, challenges such as insufficient drug loading and...
Published: 4/2/2026
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Updated: 3/30/2026
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Inventor(s):
Keywords(s):
Category(s): Technology Classifications > Disease Area > Anesthesia, Technology Classifications > Invention Type > Therapeutics > Drug Delivery
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Macrophage Immunomodulation by Mesenchymal Stem Cell Exosome Treatment and Restoration of Lung Architecture in Models of Bronchopulmonary Dysplasia
Macrophage Immunomodulation by Mesenchymal Stem Cell Exosome Treatment and Restoration of Lung Architecture in Models of Bronchopulmonary Dysplasia
Background
Bronchopulmonary dysplasia (BPD) is a chronic lung condition primarily affecting premature infants due to exposure to oxygen or mechanical ventilation impacting their immature lungs. BPD affects...
Published: 3/13/2026
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Updated: 3/13/2026
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Inventor(s):
Keywords(s):
Category(s): Technology Classifications > Disease Area > Pulmonary, Technology Classifications > Invention Type > Therapeutics, Technology Classifications > Invention Type > Therapeutics > Drug Delivery
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Therapeutic Applications of Exosomes/Microvesicles from Bone Marrow Mesenchymal Cells in Pulmonary Disease
Therapeutic Applications of Exosomes/Microvesicles from Bone Marrow Mesenchymal Cells in Pulmonary Disease
Background
Premature infants face a critical risk of developing chronic lung diseases such as bronchopulmonary dysplasia (BPD), impacting about 35-40% of those born before 29 weeks of gestation. BPD alongside pulmonary hypertension (PH) results...
Published: 3/12/2026
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Updated: 3/12/2026
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Inventor(s): Stella Kourembanas, S. Alex Mitsialis, Konstantino Sdrimas
Keywords(s):
Category(s): Technology Classifications > Disease Area > Pulmonary, Technology Classifications > Invention Type > Therapeutics > Drug Delivery, Technology Classifications > Invention Type > Therapeutics
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Intravenous Microbubbles for Oxygenation
Intravenous Microbubbles for Oxygenation
Background
Severe hypoxia, characterized by insufficient oxygen delivery, poses a critical medical challenge impacting millions globally each year. Conditions such as cardiac arrest, lung injury, airway obstruction, traumatic brain injury, and birth asphyxia often lead to rapid onset of tissue damage or organ...
Published: 3/6/2026
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Updated: 3/3/2026
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Keywords(s):
Category(s): Technology Classifications > Disease Area > Fetal/Newborn Medicine, Technology Classifications > Invention Type > Therapeutics > Drug Delivery, Technology Classifications > Disease Area > Emergency Medicine
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Acute Otitis Media, Middle Ear Infection Drug Delivery
Acute Otitis Media, Middle Ear Infection Drug Delivery
Background
Acute Otitis Media (AOM) is a prevalent childhood disease, leading to over 20 million physician visits annually in the United States. With a recurrence rate affecting one third of children by age seven, AOM poses a significant healthcare challenge. Up to 80% of children experience...
Published: 3/30/2026
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Updated: 3/3/2026
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Keywords(s):
Category(s): Technology Classifications > Disease Area > Otolaryngology, Technology Classifications > Invention Type > Therapeutics > Drug Delivery
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Thermo-sensitive penetration-enhancing formulations for trans-tympanic and transdermal drugs delivery
Thermo-sensitive penetration-enhancing formulations for trans-tympanic and transdermal drug delivery
Background
Acute otitis media is one of the most common childhood diseases in the United States and present treatment of ear infections consists of systemic oral antibiotics, however these present many issues including antibiotic resistance and gastrointestinal...
Published: 3/23/2026
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Updated: 12/5/2025
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Inventor(s): Daniel Kohane, Zipei Zhang
Keywords(s): Otitis Media
Category(s): Technology Classifications > Disease Area > Otolaryngology, Technology Classifications > Disease Area > Anesthesia, Technology Classifications > Invention Type > Therapeutics > Drug Delivery
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Enhancement of drug delivery across the blood-brain barrier for the treatment of brain diseases
Enhancement of drug delivery across the blood-brain barrier for the treatment of brain diseases
Background
The blood-brain barrier (BBB) is a critical structure that protects the brain and central nervous system (CNS) by preventing most substances from crossing into these areas from the bloodstream. This protective mechanism poses a significant challenge...
Published: 3/30/2026
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Updated: 10/6/2025
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Inventor(s): Marsha Moses, Golnaz Morad
Keywords(s):
Category(s): Technology Classifications > Disease Area > Neurology, Technology Classifications > Invention Type > Therapeutics, Technology Classifications > Invention Type > Therapeutics > Drug Delivery
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Modified liposomes for improved drug loading and sustained drug release
Modified liposomes for improved drug loading and sustained drug release
Background
Liposomes are a promising method of drug delivery, offering better properties than traditional drug delivery systems. However, despite having better site-targeting, protection from drug degradation, improved sustained or controlled release, and lower toxicity, some...
Published: 3/30/2026
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Updated: 3/28/2025
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Inventor(s): Daniel Kohane, Yang Li
Keywords(s): Analgesic/Anesthetic, Drug Delivery
Category(s): Technology Classifications > Disease Area > Anesthesia, Technology Classifications > Invention Type > Therapeutics, Technology Classifications > Invention Type > Therapeutics > Drug Delivery
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Biofilm Matrix Boosted Vaccine
Biofilm Matrix Boosted Vaccine
Background
Bacterial biofilm formation is a process in which bacteria adhere to a surface, creating single or multilayer structures. The biofilm matrix consists of exopolysaccharides, proteins, and DNA. In contrast to the conventional belief that biofilm exopolysaccharides primarily serve as adhesive materials for binding...
Published: 3/20/2026
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Updated: 3/10/2025
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Inventor(s): Paula Watnick, Julie Liao
Keywords(s):
Category(s): Technology Classifications > Disease Area > Infectious Disease, Technology Classifications > Invention Type > Therapeutics > Drug Delivery
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Aptamer as drug delivery vehicle for Site-1 Sodium Channel Blocking agents.
Aptamer as drug delivery vehicle for Site-1 Sodium Channel Blocking agents
Background
Aptamers are small, short, single-stranded molecules of DNA or RNA or peptides. They act like chemical “keys” that can find and attach to specific “locks” on certain molecules. This biological mechanism is called antibody-antigen interaction;...
Published: 3/30/2026
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Updated: 1/17/2024
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Inventor(s): Daniel Kohane, Dali Wang, Christopher Weldon, Xiangang Huang
Keywords(s):
Category(s): Technology Classifications > Disease Area > Surgery, Technology Classifications > Invention Type > Therapeutics > Drug Delivery
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