Search Results - marsha+moses

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Enhancement of drug delivery across the blood-brain barrier for the treatment of brain diseases

Enhancement of drug delivery across the blood-brain barrier for the treatment of brain diseases Background The blood-brain barrier (BBB) is a critical structure that protects the brain and central nervous system (CNS) by preventing most substances from crossing into these areas from the bloodstream. This protective mechanism poses a significant challenge...

Published: 3/30/2026 | Updated: 10/6/2025 | Inventor(s): Marsha Moses, Golnaz Morad

Keywords(s):

Category(s): Technology Classifications > Disease Area > Neurology, Technology Classifications > Invention Type > Therapeutics, Technology Classifications > Invention Type > Therapeutics > Drug Delivery

A novel antibody drug conjugate to treat pancreatic cancer

Novel Antibody Conjugate to Treat Pancreatic Cancer Background Pancreatic cancer (PC) represents 7% of all cancer mortalities and has a strikingly poor prognosis with PC patients having a 5-year survival rate of less than 8% despite recently intensified studies of immunotherapy and nanomedicine therapy. The immunosuppressive microenvironment of pancreatic...

Published: 6/26/2025 | Updated: 6/9/2023 | Inventor(s): Marsha Moses, Jing Huang, Peng Guo

Keywords(s): Common, Oncology, Therapeutic

Category(s): Technology Classifications > Invention Type, Technology Classifications > Invention Type > Therapeutics, Technology Classifications > Disease Area, Technology Classifications > Disease Area > Oncology, Technology Classifications > Invention Type > Therapeutics > Large Molecule

A rationally designed ICAM1 antibody drug conjugate for triple negative breast cancer and other ICAM1-expressing cancers

A rationally designed ICAM1 antibody drug conjugate for triple negative breast cancer and other ICAM1-expressing cancers Background Breast cancer is the most common cancer in women. It accounts for 12.5% of all cancers globally and women in the United States have a 1 in 8 chance of developing breast cancer. While the 5-year survival is about 90% for...

Published: 6/30/2025 | Updated: 6/9/2023 | Inventor(s): Marsha Moses, Peng Guo, Jing Huang, Jianmin Fang

Keywords(s): Common, Oncology, Therapeutic

Category(s): Technology Classifications > Disease Area, Technology Classifications > Disease Area > Oncology, Technology Classifications > Invention Type, Technology Classifications > Invention Type > Therapeutics, Technology Classifications > Invention Type > Therapeutics > Large Molecule

Nanoparticles Targeting Gene Editing Systems to Cancer Cells

Nanoparticles Targeting Gene Editing Systems to Cancer Cells Targeted gene therapy delivery platform for oncology indications with stable nanoparticles and no cytotoxicity Background To date, existing gene editing delivery systems involve viral vectors or cationic materials, which carry a high human safety concern. Researchers at Boston Children’s...

Published: 6/30/2025 | Updated: 5/5/2023 | Inventor(s): Marsha Moses, Peng Guo, Jiang Yang, Debra Auguste

Keywords(s): Cancer, Gene Therapy, Oncology, Viral Vector

Dual-Targeting Liposome-Based Drug Delivery System

Dual-Targeting Liposome-Based Drug Delivery System It can be used as a novel, highly precise and effective TNBC therapy and as a platform to develop targeted therapeutics for other cancers Background A major challenge in cancer treatment is discriminating malignant cancer cells from normal cells. “Cancer-targeting” liposomes have been...

Published: 3/30/2026 | Updated: 3/6/2023 | Inventor(s): Marsha Moses, Jiang Yang, Debra Auguste, Daxing Liu, Peng Guo

Keywords(s):

Category(s): Technology Classifications > Invention Type, Technology Classifications > Invention Type > Therapeutics, Technology Classifications > Invention Type > Therapeutics > Drug Delivery, Technology Classifications > Disease Area, Technology Classifications > Disease Area > Oncology